(S, S, S) -AHPC (hydrochloride)
(S, S, S) -AHPC hydrochloride is a von Hippel-Lindau (VHL) amino building block. (S, S, S) -AHPC (Compound 27) is a ligand used as a negative control for (S, R, S) -AHPC. (S, R, S) -AHPC is the VH032-based VHL ligand used in the recruitment of the VHL protein[1].
Product Specifications
CAS Number
[2115897-23-7]
Product Name Alternative
(S, S, S) -VH032-NH2 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-s-s-ahpc-hydrochloride.html
Purity
99.16
Solubility
DMSO : 62.5 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H](C[C@H](O)C1)N1C([C@@H](N)C(C)(C)C)=O)NCC2=CC=C(C(SC=N3)=C3C)C=C2.Cl
Molecular Formula
C22H31ClN4O3S
Molecular Weight
467.02
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Available Sizes
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