Talaroterphenyl A
Product Specifications
UNSPSC Description
Talaroterphenyl A (compound 1) is a p-terphenyl derivative present in the mangrove sediment-derived fungus Talaromyces sp. SCSIO 41412, which exhibits phosphodiesterase 4 (PDE4) inhibitory activity (IC50=1.2 μM). Talaroterphenyl A also exhibits anti-inflammatory and anti-fibrotic activities, significantly reducing the mRNA levels of pro-inflammatory cytokines IL-6, TNF-α, and IL-1β[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/talaroterphenyl-a.html
Smiles
OC1=C(C2=CC=CC=C2)C(OC(C)=O)=C(OC)C(C3=CC=CC=C3)=C1OC
Molecular Weight
364.39
References & Citations
[1]Cai J, et al. Discovery of Oxidized p-Terphenyls as Phosphodiesterase 4 Inhibitors from Marine-Derived Fungi[J]. Journal of Natural Products, 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163777/Talaroterphenyl-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163777/
Clinical Information
No Development Reported
Curated Selection
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