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CK2-IN-4

CK2-IN-4 (compound 5) is a protein kinase (CK2) inhibitor (IC50=8.6 µM) . CK2-IN-4 has good potential for research in the areas of cancer, viral infections and glomerulonephritis[1].

Product Specifications

CAS Number

[313985-59-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ck2-in-4.html

Purity

99.24

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C(C2=CSC(NC3=CC=CC=C3)=N2)=CC4=CC([N+]([O-])=O)=CC=C4O1

Molecular Formula

C18H11N3O4S

Molecular Weight

365.36

Precautions

H302, H315, H319

References & Citations

[1]Nakanishi I, et al. Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening. Eur J Med Chem. 2015;96:396-404.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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