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Aspalatone

Aspalatone is an orally active antiplatelet aggregant with IC50 of 180 μM. Aspalatone has antioxidant and neuroprotective activities[1][2].

Product Specifications

CAS Number

147249-33-0

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aspalatone.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(OC(C)=O)C=CC=C1)OC2=C(C)OC=CC2=O

Molecular Formula

C15H12O6

Molecular Weight

288.25

References & Citations

[1]Han BH, et al. Synthesis and antiplatelet effects of the new antithrombotic agent aspalatone with low ulcerogenicity. Arzneimittelforschung. 1994 Oct;44 (10) :1122-6.|[2]Kim HC, et al. Aspalatone, a new antiplatelet agent, attenuates the neurotoxicity induced by kainic acid in the rat. Life Sci. 1997;61 (24) :PL 373-81.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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