Retrorsine N-oxide
Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides[1][2].
Product Specifications
CAS Number
15503-86-3
UNSPSC
12352005
Hazard Statement
H300-H373
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/retrorsine-n-oxide.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(C[C@H]([C@@](O)(C(OCC1=CC2)=O)CO)C)=C\C)O[C@@]3([H])[C@]1([H])[N+]2([O-])CC3
Molecular Formula
C18H25NO7
Molecular Weight
367.39
Precautions
P260-P264-P270-P330-P405-P501
References & Citations
[1]He X, et, al. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides. J Food Drug Anal. 2017 Oct;25 (4) :984-991.|[2]Valese AC, et, al. Quantification of pyrrolizidine alkaloids in Senecio brasiliensis, beehive pollen, and honey by LC-MS/MS. J Environ Sci Health B. 2021;56 (7) :685-694.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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