Ethyl β-carboline-3-carboxylate
Ethyl β-carboline-3-carboxylate (fl-CCE) is a ligand and short-acting antagonist of benzodiazepine receptors. Ethyl β-carboline-3-carboxylate did not affect cerebellar cGMP levels when used alone, but when taken together with Diazepam, it significantly inhibited the cGMP levels that were upregulated by Diazepam[1].
Product Specifications
CAS Number
[74214-62-3]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ethyl-β-carboline-3-carboxylate.html
Purity
99.75
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)OCC
Molecular Formula
C14H12N2O2
Molecular Weight
240.26
Precautions
H315, H319, H335
References & Citations
[1]ETHYL-CARBOLINE-3-CARBOXYLATE REVERSES THE DIAZEPAM EFFECT ON CEREBELLAR CYCLIC GMP
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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