6′-Amino-D-luciferin
6’-Amino-D-luciferin is a derivative of D-luciferin (HY-12591A) with an amino group replacing the 6-hydroxyl group. 6’-Amino-D-luciferin is a natural substrate of luciferase (Luc) and can be used for IVIS imaging in cell/animal experiments[1][2][3].
Product Specifications
CAS Number
[161055-47-6]
UNSPSC
12171500
Hazard Statement
H302-H312-H332
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-amino-d-luciferin.html
Purity
98.01
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1N=C(C2=NC3=CC=C(N)C=C3S2)SC1)O
Molecular Formula
C11H9N3O2S2
Molecular Weight
279.34
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Viviani VR, et al. Bioluminescence of beetle luciferases with 6'-amino-D-luciferin analogues reveals excited keto-oxyluciferin as the emitter and phenolate/luciferin binding site interactions modulate bioluminescence colors. Biochemistry. 2014 Aug 19;53 (32) :5208-20|[2]Conley NR, et al. A selenium analogue of firefly D-luciferin with red-shifted bioluminescence emission. Angew Chem Int Ed Engl. 2012 Apr 2;51 (14) :3350-3.|[3]Kovács AK, et al. Synthesis of N-peptide-6-amino-D-luciferin Conjugates. Front Chem. 2018 Apr 19;6:120.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
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