Anticancer agent 205
Anticancer agent 205 (compound 9) is a potent anticancer agent. Anticancer agent 205 binds to G4-mtDNA target and inhibits the replication, transcription, and translation of mtDNA (mitochondrial genome) . Anticancer agent 205 causes mitochondrial dysfunction, increases ROS production, induces DNA damage and cellular senescence. Anticancer agent 205 induces apoptosis and cell cycle arrests at G0/G1 phase. Anticancer agent 205 has the potential for the research of colorectal cancer[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-205.html
Solubility
10 mM in DMSO
Smiles
C12=CC=CC=C1C=CC(/C=C/C3=CC=C(C=C3)N4CCCCC4)=[N+]2CCCCCCCC[N+]5=C(C=CC6=C5C=CC=C6)/C=C/C7=CC=C(C=C7)N8CCCCC8.[I-].[I-]
Molecular Formula
C52H60I2N4
Molecular Weight
994.87
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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