Forskolin (Standard)
Forskolin (Standard) is the analytical standard of Forskolin. This product is intended for research and analytical applications. Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase[1]. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy[4][5].
Product Specifications
CAS Number
66575-29-9
Product Name Alternative
Coleonol (Standard) ; Colforsin (Standard) ; HL 362 (Standard)
UNSPSC
12352005
Target
Adenylate Cyclase; Autophagy; FXR; Organoid; PKC; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Epigenetics; GPCR/G Protein; Metabolic Enzyme/Protease; Others; Stem Cell/Wnt; TGF-beta/Smad
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Endocrinology; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/forskolin-standard.html
Purity
98.54
Smiles
O=C1[C@@]2(O)[C@]([C@@H](OC(C)=O)[C@@H](O)[C@@]3([H])C(C)(C)CC[C@H](O)[C@@]32C)(C)O[C@@](C)(C=C)C1
Molecular Formula
C22H34O7
Molecular Weight
410.50
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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