Bicyclomycin benzoate

Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.

Product Specifications

CAS Number

[37134-40-0]

Product Name Alternative

FR2054

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Bicyclomycin-benzoate.html

Concentration

10mM

Purity

99.78

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]([C@](NC1=O)(OCCC2=C)C(N[C@]12O)=O)[C@@](C)(O)COC(C3=CC=CC=C3)=O

Molecular Formula

C19H22N2O8

Molecular Weight

406.39

References & Citations

[1]Tanaka N, et al. Mechanism of action of bicyclomycin. J Antibiot (Tokyo) . 1976 Feb;29 (2) :155-68.|[2]Kohn H, et al. The molecular basis for the mode of action of bicyclomycin. Curr Drug Targets Infect Disord. 2005 Sep;5 (3) :273-95.|[3]Park HG, et al. Bicyclomycin and dihydrobicyclomycin inhibition kinetics of Escherichia coli rho-dependent transcription termination factor ATPase activity. Arch Biochem Biophys. 1995 Nov 10;323 (2) :447-54.|[4]Nishida M. et al. Bicyclomycin, a new antibiotic. IV. Absorption, excretion and tissue distribution. J Antibiot (Tokyo) . 1972 Oct;25 (10) :594-601.