MitoBloCK-11
MitoBloCK-11 is a new small molecule with a protein-binding target, Seo1. MitoBloCK-11 plays an important role in the delivery of PINK1 pathway. MitoBloCK-11 can be used in the study of autosomal recessive Parkinson's disease[1].
Product Specifications
CAS Number
[413606-16-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PINK1/Parkin
Type
Reference compound
Related Pathways
Autophagy; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mitoblock-11.html
Purity
99.28
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N/N=C/C1=CC=C([N+]([O-])=O)S1)COC2=C3C=CC=CC3=C(Br)C=C2
Molecular Formula
C17H12BrN3O4S
Molecular Weight
434.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Conti Michael, et al. Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy.2018.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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