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MitoBloCK-11

MitoBloCK-11 is a new small molecule with a protein-binding target, Seo1. MitoBloCK-11 plays an important role in the delivery of PINK1 pathway. MitoBloCK-11 can be used in the study of autosomal recessive Parkinson's disease[1].

Product Specifications

CAS Number

413606-16-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PINK1/Parkin

Type

Reference compound

Related Pathways

Autophagy; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mitoblock-11.html

Purity

99.28

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N/N=C/C1=CC=C([N+]([O-])=O)S1)COC2=C3C=CC=CC3=C(Br)C=C2

Molecular Formula

C17H12BrN3O4S

Molecular Weight

434.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Conti Michael, et al. Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy.2018.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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