EcDsbB-IN-10
EcDsbB-IN-10 (compound 12) is an inhibitor of EcDsbB (E. coli DsbB) enzyme, with a Ki of 0.8 nM and an IC50 of 18.85 nM[1].
Product Specifications
CAS Number
[112749-52-7]
Product Name Alternative
(±)-Norverapamil (hydrochloride); D591 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H332, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ecdsbb-in-10.html
Purity
98.71
Solubility
DMSO : 3 mg/mL (ultrasonic; warming)
Smiles
O=C1C(Cl)=C(C=NN1CC2=CC=CC=C2Cl)Cl
Molecular Formula
C11H7Cl3N2O
Molecular Weight
289.55
Precautions
H302, H315, H319, H332, H335
References & Citations
[1]Landeta C, et al. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nat Chem Biol. 2015 Apr;11 (4) :292-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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