Doxofylline-d4
Product Specifications
UNSPSC Description
Doxofylline-d4 is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV[1][2].
Target Antigen
Adenosine Receptor; Isotope-Labeled Compounds; Phosphodiesterase (PDE)
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein;Metabolic Enzyme/Protease;Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
C(N1C2=C(N(C)C(=O)N(C)C2=O)N=C1)C3OC(C(O3)([2H])[2H])([2H])[2H]
Molecular Weight
270.28
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Shukla D, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
1346599-13-0
Available Sizes
Curated Selection
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