NMT-IN-1
NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis[1].
Product Specifications
CAS Number
326879-46-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nmt-in-1.html
Purity
98.0
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
O=C1N(CC2=NC=CC=C2)C(C3=CC=CC=C3)SC1
Molecular Formula
C15H14N2OS
Molecular Weight
270.35
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Spinks D, et, al. Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. ChemMedChem. 2015 Nov;10 (11) :1821-36.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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