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NMT-IN-1

NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis[1].

Product Specifications

CAS Number

326879-46-3

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nmt-in-1.html

Purity

98.0

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

O=C1N(CC2=NC=CC=C2)C(C3=CC=CC=C3)SC1

Molecular Formula

C15H14N2OS

Molecular Weight

270.35

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Spinks D, et, al. Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. ChemMedChem. 2015 Nov;10 (11) :1821-36.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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