Recombinant Human Tumor necrosis factor receptor superfamily member 17 protein (TNFRSF17) (Active)

Receptor for TNFSF13B, BLyS, BAFF and TNFSF13, APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}.

Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng, ml, corresponding to a specific activity of 2.5 104 IU, mg in the presence of 100 ng, ml human APRIL.

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.