Lenampicillin (hydrochloride)

Lenampicillin hydrochloride (KBT 1585 hydrochloride) is an orally active proagent of Ampicillin and is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins (transpeptidase) . Lenampicillin hydrochloride has improved absorption and decreased side effects compares to Ampicillin and is applied in the investigation of the suppurative skin and soft tissue infection [1] [2] [3].

Product Specifications

CAS Number

[80734-02-7]

Product Name Alternative

KBT 1585 hydrochloride

UNSPSC

12352005

Target

Bacterial; Penicillin-binding protein (PBP)

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/Lenampicillin-hydrochloride.html

Purity

99.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)([H])SC1(C)C)OCC(OC4=O)=C(O4)C.Cl

Molecular Formula

C21H24ClN3O7S

Molecular Weight

497.95

References & Citations

[1]FUMIO OGINO, et al. ACUTE TOXICITY OF LENAMPICILLIN HYDROCHLORIDE (KBT-1585) IN MICE, RATS AND DOGS|[2]Yamabe S, et al. Non-mutagenicity of KBT-1585, a novel ester of ampicillin.Chemioterapia. 1984 Feb;3 (1) :60-2.|[3]Fujita K, et al. Clinical evaluation of lenampicillin in the treatment of superficial suppurative skin and soft tissue infection. A double-blind study comparing amoxicillin.Jpn J Antibiot. 1985 Jul;38 (7) :1794-818.