Cilagicin
Cilagicin, a dodeca-lipodepsipeptide, is a Gram-positive active antibiotic. Cilagicin has a dual polyprenyl phosphate binding mechanism that impedes resistance development[1].
Product Specifications
UNSPSC
12352209
Target
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cilagicin.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCC(N[C@H](CO)C(N[C@@H]1C(N[C@H](CCN)C(N[C@@H](CC(O)=O)C(NCC(N[C@H](CC(N)=O)C(N[C@H](CC(O)=O)C(NCC(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](C(C)C)C(N[C@@H](CCN)C(N[C@@H](CC3=CC=CC=C3)C(O[C@@H]1C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C68H103N15O21
Molecular Weight
1466.63
References & Citations
[1]Adam F Rosenzweig, et al. A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates. ACS Infect Dis. 2023 Dec 8;9 (12) :2394-2400.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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