HS024
HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake[1].
Product Specifications
CAS Number
212370-59-7
UNSPSC
12352209
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hs024.html
Solubility
10 mM in DMSO
Smiles
[Ac-C-{Nle}-RH-{D-2Nal}-RWGC-NH2(Disulfidebridge:Cys1-Cys9)]
Molecular Formula
C58H79N19O10S2
Molecular Weight
1266.50
References & Citations
[1]Kask A, et al. Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024) : evaluation in vitro and in vivo. Endocrinology. 1998;139 (12) :5006-5014.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MC4R
Available Sizes
Frequently Asked Questions
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