(1R,2R) -1-Aminoindan-2-ol

(1R,2R) -1-Aminoindan-2-ol is the isomer of (1S,2R) -1-Aminoindan-2-ol (HY-W002530), and can be used as a biological material or organic compound for life science related research. (1R,2R) -1-Aminoindan-2-ol can be used as a starting material to prepare an indene-based chiral auxiliary that is used in the aldol reaction. (1R,2R) -1-Aminoindan-2-ol can be used as a starting material in the synthesis of oxazoline-alcohol ligands[1][2][3][4].

Product Specifications

CAS Number

[163061-73-2]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1r-2r-1-aminoindan-2-ol.html

Purity

99.70

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](C2=C(C1)C=CC=C2)N

Molecular Formula

C9H11NO

Molecular Weight

149.19

Precautions

H315, H319, H335

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.|[3]Osorio-Lozada, A., & Olivo, H. F. (2008) . Indene-based thiazolidinethione chiral auxiliary for propionate and acetate aldol additions. Organic letters, 10 (4), 617–620. |[4]Timothy Noël, et al., Efficient one-step synthesis of chiral bidentate oxazoline-alcohol ligands via a cyclic imidate ester rearrangement, Tetrahedron: Asymmetry, Volume 20, Issue 17, 2009, Pages 1962-1968, ISSN 0957-4166.