DP-b99

DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.

Product Specifications

CAS Number

222315-88-0

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dp-b99.html

Purity

95.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(OCCOCCCCCCCC)=O)CC(O)=O)CC(O)=O)OCCOCCCCCCCC

Molecular Formula

C42H64N2O12

Molecular Weight

788.96

References & Citations

[1]Kalendarev T, Zupkovitz G, Ioffe V. The unusual gradient elution for reversed phase HPLC of a strong chelator as an active drug substance. J Pharm Biomed Anal. 2001;24 (5-6) :967-975. |[2]Diener HC, Schneider D, Lampl Y, Bornstein NM, Kozak A, Rosenberg G. DP-b99, a membrane-activated metal ion chelator, as neuroprotective therapy in ischemic stroke. Stroke. 2008;39 (6) :1774-1778.