Recombinant Human FGL1 (C-6His)
Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a 6His tag at the C-terminus.
Product Specifications
Background
Fibrinogen-like protein 1 (FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .
Synonyms
Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1
UniProt
Q08830
Accession Number
Q08830
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Purity
Greater than 90% as determined by reducing SDS-PAGE.
Molecular Weight
35 KDa
Shipping Conditions
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Notes
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Observed Molecular Weight
35 KDa, reducing conditions
Other Product Names
Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1
CAS Number
9000-83-3
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