N-Me-L-Ala-maytansinol

[77668-69-0]

12352203

ADC Payload

ADC Related

Antibody-drug Conjugate/ADC Related

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/n-me-l-ala-maytansinol.html

10mM

99.89

DMSO : 100 mg/mL (ultrasonic)

C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)NC)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

C32H44ClN3O9

650.16

[1]Nittoli T, et al. Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids. Bioorg Med Chem. 2018 May 15;26 (9) :2271-2279.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

ADC Related

No Development Reported

Maytansinoids