N-Me-L-Ala-maytansinol
Product Specifications
UNSPSC Description
N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used for making antibody-drug conjugate (ADC)[1].
Target Antigen
ADC Cytotoxin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-me-l-ala-maytansinol.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)NC)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Molecular Weight
650.16
References & Citations
[1]Nittoli T, et al. Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids. Bioorg Med Chem. 2018 May 15;26(9):2271-2279.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126663/N-Me-L-Ala-maytansinol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126663/N-Me-L-Ala-maytansinol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
77668-69-0
Available Sizes
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