Fructosyl-lysine (dihydrochloride)

Fructosyl-lysine (Fructoselysine) dihydrochloride is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine dihydrochloride is the precursor to glucosepane, a lysine-arginine protein cross-link that can be an indicator in diabetes detection[1].

Product Specifications

CAS Number

[96192-35-7]

Product Name Alternative

Fructoselysine (dihydrochloride)

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fructosyl-lysine-dihydrochloride.html

Purity

95.0

Solubility

H2O : 40 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N[C@H](C(O)=O)CCCCNCC([C@@H](O)[C@H](O)[C@H](O)CO)=O.[H]Cl.[H]Cl

Molecular Formula

C12H26Cl2N2O7

Molecular Weight

381.25

References & Citations

[1]Rabbani N, et al. Hidden complexities in the measurement of fructosyl-lysine and advanced glycation end products for risk prediction of vascular complications of diabetes. Diabetes. 2015 Jan;64 (1) :9-11.|[2]Karachalias N, et al. Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochem Soc Trans. 2003 Dec;31 (Pt 6) :1423-5.