Ataluren (Standard)
Ataluren (Standard) is the analytical standard of Ataluren. This product is intended for research and analytical applications. Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor.
Product Specifications
CAS Number
[775304-57-9]
Product Name Alternative
PTC124 (Standard)
UNSPSC
12352005
Target
Autophagy; CFTR; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/ataluren-standard.html
Purity
98.59
Smiles
O=C(C1=CC=CC(C2=NOC(C3=CC=CC=C3F)=N2)=C1)O
Molecular Formula
C15H9FN2O3
Molecular Weight
284.24
References & Citations
[1]Pettit RS, et al. CFTR Modulators for the Treatment of Cystic Fibrosis. P T. 2014 Jul;39 (7) :500-11.|[2]Welch EM, et al. PTC124 targets genetic disorders caused by nonsense mutations. Nature, 2007, 447 (7140), 87-91.|[3]Miller JN, et al. The novel Cln1 (R151X) mouse model of infantile neuronal ceroid lipofuscinosis (INCL) for testing nonsense suppression therapy. Hum Mol Genet. 2015 Jan 1;24 (1) :185-96.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
ABP-PAB-10229 100 ug
Kinase D-interacting substance of 220 kDa (KIDINS220) polyclonal antibody
Ask
View Details 
MBS6368142-01 0.2 mL
ZRSR1, CT (ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1P, U2AF1RS1, U2AFBPL, U2 small nuclear ribonucleoprotein auxiliary factor 35kD subunit-related protein 1, CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1, U2(RNU2) small nuclear RNA au
Ask
View Details MBS6368142-02 5x 0.2 mL
ZRSR1, CT (ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1P, U2AF1RS1, U2AFBPL, U2 small nuclear ribonucleoprotein auxiliary factor 35kD subunit-related protein 1, CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1, U2(RNU2) small nuclear RNA au
Ask
View Details MBS1448225-01 0.5 mg (E-Coli)
Recombinant Mouse Collagen alpha-1 (XXIII) chain (Col23a1), partial
Ask
View Details MBS1448225-02 0.05 mg (Baculovirus)
Recombinant Mouse Collagen alpha-1 (XXIII) chain (Col23a1), partial
Ask
View Details