5Me3F4AP
5Me3F4AP is a potent blocker of potassium channel, with the IC50 of 220 μM to 693 μM when the pH is increased from 6.4 to 9.1. 5Me3F4AP has the potential to cross the blood-brain barrier and potential application in positron emission tomography (PET) [1].
Product Specifications
CAS Number
13958-85-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5me3f4ap.html
Purity
99.55
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=C(F)C=NC=C1C
Molecular Formula
C6H7FN2
Molecular Weight
126.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Sun Y, et al. Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine. Sci Rep. 2024 May 15;14 (1) :11105.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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