Ro 363 (hydrochloride)
Ro 363 hydrochloride, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. Ro 363 hydrochloride is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility[1][2][3].
Product Specifications
CAS Number
250580-70-2
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ro-363-hydrochloride.html
Purity
95.16
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(OCC(O)CNCCC2=CC=C(OC)C(OC)=C2)C=C1O.[H]Cl
Molecular Formula
C19H26ClNO6
Molecular Weight
399.87
References & Citations
[1]Maccarrone C, et al. Comparison of the Arrhythmogenic Actions of (-) -Isoprenaline, Dobutamine and the selective beta 1-adrenoceptor agonist, (+/-) - (1-[3',4'-dihydroxyphenoxy] -2-hydroxy-[3",4"-dimethoxy phenethylamino]-propane) -oxalate (Ro 363) . Arzneimittelforschung. 1985;35 (3) :592-8.|[2]Iakovidis D, et al. In vitro activity of RO363, a beta1-adrenoceptor selective agonist. Br J Pharmacol. 1980 Apr;68 (4) :677-85.|[3]Einstein R, et al. Comparison of the cardiac effects of beta-adrenoreceptor agonists in anaesthetised and conscious dogs. J Auton Pharmacol. 1986 Mar;6 (1) :9-14.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471722-100 1x 100 µL
Desmin (Muscle Cell Marker) (D33), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: OTI1D1]](https://cdn.genprice.uk/products/937/68dd18b9061270361e908228/imageurl/cf808035.webp)
CF808035 100 µg
PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: OTI1D1]
Sign In for Pricing
View Details 
![Elab Fluor® 488 Anti-Human CD11a Antibody[TS1/22.1.1.13]](https://cdn.genprice.uk/products/763/68dd14a5061270361e7d181b/imageurl/e-ab-f1055l.webp)
E-AB-F1055L-01 20 Tests
Elab Fluor® 488 Anti-Human CD11a Antibody[TS1/22.1.1.13]
Sign In for Pricing
View Details E-AB-F1055L-02 100 Tests
Elab Fluor® 488 Anti-Human CD11a Antibody[TS1/22.1.1.13]
Sign In for Pricing
View Details