(S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin
Product Specifications
UNSPSC Description
(S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-20 (HY-163873)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-o-cf3-co-cyclohexene-bpin.html
Smiles
O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(OC(F)(F)F)C=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(C4CC=C(B5OC(C)(C)C(C)(C)O5)CC4)=O
Molecular Weight
748.66
References & Citations
[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163950/S-R-S-AHPC-O-CF3-CO-cyclohexene-Bpin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163950/
Clinical Information
No Development Reported
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