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(S, R, S) -AHPC-O-CF3-CO-cyclohexene-Bpin

(S, R, S) -AHPC-O-CF3-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S, R, S) -AHPC-O-CF3-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-20 (HY-163873) [1].

Product Specifications

UNSPSC

12352211

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-o-cf3-co-cyclohexene-bpin.html

Smiles

O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(OC(F)(F)F)C=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(C4CC=C(B5OC(C)(C)C(C)(C)O5)CC4)=O

Molecular Formula

C36H48BF3N4O7S

Molecular Weight

748.66

References & Citations

[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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