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Revefenacin (Standard)

Revefenacin (Standard) is the analytical standard of Revefenacin. This product is intended for research and analytical applications. Revefenacin (TD-4208; GSK1160724) is a potent mAChR antagonist; has a high affinity on M3 receptor with a Ki of 0.18 nM.

Product Specifications

CAS Number

[864750-70-9]

Product Name Alternative

TD-4208 (Standard) ; GSK1160724 (Standard)

UNSPSC

12352005

Target

MAChR; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/revefenacin-standard.html

Smiles

O=C(OC1CCN(CCN(C(C2=CC=C(CN3CCC(C(N)=O)CC3)C=C2)=O)C)CC1)NC4=CC=CC=C4C5=CC=CC=C5

Molecular Formula

C35H43N5O4

Molecular Weight

597.75

References & Citations

[1]Steinfeld T, et al. In vitro characterization of TD-4208, a lung-selective and long-acting muscarinic antagonist bronchodilator (Abstract) . Am J Respir Crit Care Med 179:A4553.|[2]Pulido-Rios MT, et al. In vivo pharmacological characterization of TD-4208, a novel lung-selective inhaled muscarinic antagonist with sustained bronchoprotective effect in experimental animal models. J Pharmacol Exp Ther. 2013 Aug;346 (2) :241-50.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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