FUBP1-IN-1

FUBP1-IN-1 is a potent FUSE binding protein 1 (FUBP1) inhibitor which interferes with the binding of FUBP1 to its single stranded target DNA FUSE sequence , with an IC50 value of 11.0 μM[1].

Product Specifications

CAS Number

[883003-62-1]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fubp1-in-1.html

Purity

99.72

Solubility

DMSO : 16.67 mg/mL (ultrasonic)

Smiles

COC1=C(OC)C=C(C2=NC3=CC(C4=CC=CS4)=NN3C(C(F)(F)F)=C2)C=C1

Molecular Formula

C19H14F3N3O2S

Molecular Weight

405.39

References & Citations

[1]Hauck S, et al. Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors. Bioorg Med Chem. 2016 Nov 15;24 (22) :5717-5729.