Tuberin/TSC2 (phospho-Ser1254) rabbit pAb
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P49815
Swiss Prot
P49815
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized phosho peptide around human Tuberin (Ser1254)
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Molecular Weight
200kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
200kD
Fragment
IgG
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.
Other Product Names
Tuberin (Tuberous sclerosis 2 protein)
Gene ID (Human)
7249
Available Sizes
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