Betulonic acid

Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities[2][1][3][4].

Product Specifications

CAS Number

[4481-62-3]

Product Name Alternative

Betunolic acid; Liquidambaric acid; (+) -Betulonic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

HSV; Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Betulonic-acid.html

Concentration

10mM

Purity

98.77

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1(C)C(CC[C@]2(C)[C@@]3([H])CC[C@]4([H])[C@@]5([H])[C@H](C(C)=C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O

Molecular Formula

C30H46O3

Molecular Weight

454.68

Precautions

H302, H315, H319, H335

References & Citations

[1]Bastos DZL, et, al. Biotransformation of betulinic and betulonic acids by fungi. Phytochemistry. 2007 Mar;68 (6) :834-9.|[2]Yang SJ, et, al. Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents. Eur J Med Chem. 2015;96:58-65.|[3]Sá MS, et, al. Antimalarial activity of betulinic acid and derivatives in vitro against Plasmodium falciparum and in vivo in P. berghei-infected mice. Parasitol Res. 2009 Jul;105 (1) :275-9.|[4]Pavlova NI, et, al. Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses. Fitoterapia. 2003 Jul;74 (5) :489-92.