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5-FAM-Alkyne

5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP) [1]. 5-FAM-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[510758-19-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-fam-alkyne.html

Purity

95.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC2=C1C3(C(C=CC(C(NCC#C)=O)=C4)=C4C(O3)=O)C(C=CC(O)=C5)=C5O2

Molecular Formula

C24H15NO6

Molecular Weight

413.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Mengmeng Zhao, et al. A Sensitive Fluorescence Biosensor for Alkaline Phosphatase Activity Based on the Cu (II) -dependent DNAzyme. Anal Chim Acta. 2016 Dec 15;948:98-103.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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