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1,4-DPCA

1,4-DPCA is a competitive inhibitor of prolyl 4-hydroxylase. It inhibits isolated chick prolyl 4-hydroxylase and procollagen synthesis in human foreskin fibroblasts with an IC₅₀ value of 3.6 and 2.4 µM, respectively. It also inhibits factor inhibiting HIF (FIH) with an IC₅₀ of 60 μM. Inhibitors of prolyl 4-hydroxylase maybe useful in controlling excess collagen deposition in pathological fibrosis.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

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