Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DLin-KC2-DMA

DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs) . DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP) . DLin-KC2-DMA can be used in siRNA delivery studies[1][2].

Product Specifications

CAS Number

1190197-97-7

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Liposome

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/DLin-KC2-DMA.html

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

CCCCC/C=C\C/C=C\CCCCCCCCC1(CCCCCCCC/C=C\C/C=C\CCCCC)OC(CCN(C)C)CO1

Molecular Formula

C43H79NO2

Molecular Weight

642.09

Precautions

H315, H319

References & Citations

[1]Miller AD, et al. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10 (6) :781-811.|[2]Basha G, et al. Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells. Mol Ther. 2011 Dec;19 (12) :2186-200.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Tgfa Mouse Gene Knockout Kit (CRISPR)
KN517481 1 Kit

Tgfa Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Tissue FFPE Sections, Kidney
CS716478 5x 5 µm

Tissue FFPE Sections, Kidney

Sign In for Pricing
View Details
SAFB Recombinant Rabbit Monoclonal Antibody [JE64-94]
HA721085 100 µL

SAFB Recombinant Rabbit Monoclonal Antibody [JE64-94]

Sign In for Pricing
View Details
Slc12a4 Mouse Gene Knockout Kit (CRISPR)
KN515864 1 Kit

Slc12a4 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
SORBS1 (NM_001034955) Human Recombinant Protein
TP324759L 1 mg

SORBS1 (NM_001034955) Human Recombinant Protein

Sign In for Pricing
View Details
SEC14L1 (NM_001143999) Human Recombinant Protein
TP326540L 1 mg

SEC14L1 (NM_001143999) Human Recombinant Protein

Sign In for Pricing
View Details