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DNA polymerase-IN-5

DNA polymerase-IN-5 (compound 42) is a broad-spectrum herpes antiviral. DNA polymerase-IN-5 against both CMV and VZV infection with IC50 values of 6.6 and 4.8 μM[1].

Product Specifications

UNSPSC

12352005

Target

CMV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dna-polymerase-in-5.html

Purity

99.44

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(C[C@@H]2NC(OC2)=O)C(OC)=C1)CC3=CC=C(C(F)(F)F)C=C3

Molecular Formula

C20H19F3N2O4

Molecular Weight

408.37

References & Citations

[1]Michael A. Plotkin, et al. Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure–Activity Relationships. ACS Medicinal Chemistry Letters. 2024.9.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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