LCS-1
LCS-1 is a superoxide dismutase 1 (SOD1) inhibitor. LCS-1 inhibits SOD1 activity with an IC50 value of 1.07 μM. LCS-1 induces the early- and late-stage apoptosis of multiple myeloma (MM.1S) cells[1][2][3].
Product Specifications
CAS Number
[41931-13-9]
Product Name Alternative
MK-0364 (racemate),R816
UNSPSC
12352005
Hazard Statement
H301, H319
Target
Apoptosis; SOD
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lcs-1.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C(Cl)=C(Cl)C=NN1C2=CC=CC(C)=C2
Molecular Formula
C11H8Cl2N2O
Molecular Weight
255.10
Precautions
H301, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115445/LCS-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115445/LCS-1-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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