Froxiprost
Froxiprost (ONO-995) is a PGF2α analogue. Froxiprost stimulates thymidine uptake, 1,2 diacylglycerol (1,2-DAG) accumulation, and phosphorylcholine formation in osteoblast-like MC3T3-E1 cells[1].
Product Specifications
CAS Number
62559-74-4
Product Name Alternative
ONO-995
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/froxiprost.html
Smiles
COC(/C=C/C/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)COC2=CC(C(F)(F)F)=CC=C2)=O
Molecular Formula
C24H29F3O6
Molecular Weight
470.48
References & Citations
[1]Sakai T, et al. Involvement of phosphatidylcholine hydrolysis by phospholipase C in prostaglandin F2alpha-induced 1,2-diacylglycerol formation in osteoblast-like MC3T3-E1 cells. J Bone Miner Metab. 2004;22 (3) :198-206.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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