Montirelin

Montirelin (NS 3) is an analog of thyrotropin-releasing hormone (TRH), and exhibits high affinity to TRH receptors. Montirelin exhibits potent effects to central nervous system (CNS) [1].

Product Specifications

CAS Number

[90243-66-6]

Product Name Alternative

NS 3

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Thyroid Hormone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/montirelin.html

Smiles

O=C(N)[C@H]1N(C([C@H](CC2=CN=CN2)NC([C@H](CS[C@@H]3C)NC3=O)=O)=O)CCC1

Molecular Formula

C17H24N6O4S

Molecular Weight

408.48

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Urayama A, et al., Brain receptor binding characteristics and pharmacokinetic-pharmacodynamic analysis of thyrotropin-releasing hormone analogues. Life Sci. 2001 Dec 28;70 (6) :647-57.