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Acetophenazine (dimaleate)

Acetophenazine dimaleate, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine dimaleate primarily blocks dopamine D2 receptors in the brain. Acetophenazine dimaleate can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].

Product Specifications

CAS Number

5714-00-1

UNSPSC

12352005

Hazard Statement

H319

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Acetophenazine_dimaleate.html

Purity

99.90

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(C(C=C1N2CCCN3CCN(CCO)CC3)=CC=C1SC4=C2C=CC=C4)=O.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O

Molecular Formula

C31H37N3O10S

Molecular Weight

643.70

Precautions

H319

References & Citations

[1]Hollister LE, et al. Acetophenazine and diazepam in anxious depressions. Arch Gen Psychiatry. 1971 Mar;24 (3) :273-8.|[2]Azam Bazrafshan, et al. Acetophenazine versus chlorpromazine for schizophrenia. Cochrane Database of Systematic Reviews. 2015, Issue 4.|[3]KNIGHT WR, HOLTZ JR, SPROGIS GR. ACETOPHENAZINE AND FIGHTING BEHAVIOR IN MICE. Science. 1963 Aug 30;141 (3583) :830-1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

D2 Receptor

Available Sizes

Frequently Asked Questions

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