DMH4
Product Specifications
UNSPSC Description
DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM[1].
Target Antigen
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dmh4.html
Purity
98.98
Solubility
DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
C12=C(C3=CC=CC=C3)C=NN1C=C(C4=CC=C(OCCN5CCOCC5)C=C4)C=N2
Molecular Weight
400.47
References & Citations
[1]Hao J, et al. In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. ACS Chem Biol. 2010 Feb 19;5(2):245-53.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108443/DMH4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108443/DMH4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
515880-75-8
Available Sizes
Curated Selection
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