Penciclovir
Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 μg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse[1][2].
Product Specifications
CAS Number
39809-25-1
Product Name Alternative
BRL 39123; VSA 671
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Penciclovir.html
Purity
99.92
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC(N)=NC2=C1N=CN2CCC(CO)CO
Molecular Formula
C10H15N5O3
Molecular Weight
253.26
Precautions
H302, H315, H319, H335
References & Citations
[1]M.R. Boyd, et al. Penciclovir: a review of its spectrum of activity, selectivity, and cross-resistance pattern. Antiviral Chemistry and Chemotherapy, 1993, (1) : 3-11.|[2]de la Fuente R, et al. The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model. Antiviral Res. 1992 May;18 (1) :77-89.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HSV-1; HSV-2
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