NCL, Human (P.pastoris, His)

Nucleolar protein (NCL) is the major nucleolar protein in actively growing eukaryotic cells and is associated with intranucleolar chromatin and preribosomal granules. It induces chromatin decondensation by binding to histone H1 and plays a role in pre-rRNA transcription, ribosome assembly, and potential transcription elongation. NCL Protein, Human (P.pastoris, His) is the recombinant human-derived NCL protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of NCL Protein, Human (P.pastoris, His) is 481 a.a., with molecular weight (post-translational modification form) of ~72 KDa.

VKLAKAGKNQ GDPKKMAPPP KEVEEDSEDE EMSEDEEDDS SGEEVVIPQK KGKKAAATSA KKVVVSPTKK VAVATPAKKA AVTPGKKAAA TPAKKTVTPA KAVTTPGKKG ATPGKALVAT PGKKGAAIPA KGAKNGKNAK KEDSDEEEDD DSEEDEEDDE DEDEDEDEIE PAAMKAAAAA PASEDEDDED DEDDEDDDDD EEDDSEEEAM ETTPAKGKKA AKVVPVKAKN VAEDEDEEED DEDEDDDDDE DDEDDDDEDD EEEEEEEEEE PVKEAPGKRK KEMAKQKAAP EAKKQKVEGT EPTTAFNLFV GNLNFNKSAP ELKTGISDVF AKNDLAVVDV RIGMTRKFGY VDFESAEDLE KALELTGLKV FGNEIKLEKP KGKDSKKERD ARTLLAKNLP YKVTQDELKE VFEDAAEIRL VSKDGKSKGI AYIEFKTEAD AEKTFEEKQG TEIDGRSISL YYTGEKGQNQ DYRGGKNSTW S