Steviolbioside

Steviolbioside is a sweetener and also an important pharmaceutical intermediate. Steviolbioside can inhibit the proliferation of various tumor cells. Steviolbioside has an MIC of 3.8 µg/mL for Mycobacterium tuberculosis. Steviolbioside also has antidiabetic activity. Steviolbioside can be used in the research of tuberculosis, diabetes and tumors such as breast cancer[1][2][3].

Product Specifications

CAS Number

[41093-60-1]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Bacterial; Drug Intermediate

Type

Natural Products

Related Pathways

Anti-infection; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/steviolbioside.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@]12[C@@]3([H])[C@@](C4)(CC[C@]1([H])[C@@](C)(CCC2)C(O)=O)C[C@@](C4=C)(O[C@@]5([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O5)O)O[C@]6([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)CO)CC3

Molecular Formula

C32H50O13

Molecular Weight

642.73

Precautions

H302, H312, H332

References & Citations

[1]Chen JM, et al. Production of a bioactive sweetener steviolbioside via specific hydrolyzing ester linkage of stevioside with a β-galactosidase. Food Chem. 2016 Apr 1;196:155-60.|[2]Myint KZ, et al. Structural dependence of antidiabetic effect of steviol glycosides and their metabolites on streptozotocin-induced diabetic mice. J Sci Food Agric. 2020 Aug;100 (10) :3841-3849.|[3]Kataev VE, et al. [Synthesis and antituberculosis activity of the derivatives of glycoside steviolbioside from the plant Stevia rebaudiana and diterpenoid isosteviol containing hydrazone, hydrazide and pyridinoyl moieties]. Bioorg Khim. 2011 Jul-Aug;37 (4) :542-51.