Recombinant Human Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), partial (Active)
Product Specifications
Product Name Alternative
B-cell maturation protein (CD_antigen: CD269) (BCM) (BCMA)
Abbreviation
Recombinant Human TNFRSF17 protein, partial (Active)
Gene Name
TNFRSF17
UniProt
Q02223
Expression Region
1-54aa
Organism
Homo sapiens (Human)
Target Sequence
MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNA
Tag
C-terminal mFc-tagged
Type
Active Protein & In Stock Protein
Source
Mammalian cell
Field of Research
Cancer
Relevance
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Purity
Greater than 95% as determined by SDS-PAGE.
Activity
Yes
Bioactivity
①Measured by its binding ability in a functional ELISA. Immobilized Anti-TNFRSF17 recombinant antibody (CSB-RA023974MA3HU) at 2 μg/mL can bind Human TNFRSF17 protein. The EC50 is 1.745-1.901 ng/mL. ②Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF13B protein (CSB-MP897523HU1-B) at 2 μg/mL can bind Human TNFRSF17 protein. The EC50 is 2.232-2.579 ng/mL.
Form
Lyophilized powder
Buffer
Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
35.2 kDa
References & Citations
"The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed." Laabi Y., Gras M.P., Brouet J.C., Berger R., Larsen C.J., Tsapis A. Nucleic Acids Res. 22:1147-1154 (1994)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial
Available Sizes
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