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ATG4a Rabbit rabbit pAb

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq, Mar 2016],

Product Specifications

Background

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq, Mar 2016]

Synonyms

Cysteine protease ATG4A (EC 3.4.22.-;AUT-like 2 cysteine endopeptidase;Autophagin-2;Autophagy-related cysteine endopeptidase 2;Autophagy-related protein 4 homolog A;hAPG4A)

Gene ID

115201

UniProt

Q8WYN0

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Protein of ATG4a

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF

Validated Applications

IHC,IF

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1:50-300

Molecular Weight

45kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20829-1.pdf

Observed Molecular Weight

45 kD

Subcellular Location

Cytoplasm .

Other Product Names

Cysteine protease ATG4A (EC 3.4.22.-; AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A)

Gene ID (Human)

115201

SwissProt (Human)

Q8WYN0

Available Sizes

Curated Selection

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