PE-Labeled Human ACE2 / ACEH Protein, His TagStar Staining
Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.
Product Specifications
Background
Specifications
This protein carries a polyhistidine tag at the C-terminus.
Accession Number
Q9BYF1-1
Expression Region
Gln 18 - Ser 740
Host
HEK293
Target
ACE2
Conjugation
PE Labeled
Tag
C-10xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Bioactivity
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
97.9 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C, avoid light
Package Size
200ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q9BYF1-1
Preservative
Trehalose
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