LOM612

LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells[1].

Product Specifications

CAS Number

[2173232-79-4]

UNSPSC

12352005

Target

FOXO

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/LOM612.html

Purity

98.85

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=C(SN=C2N(C)C)C(C3=CC=CC=C31)=O

Molecular Formula

C13H10N2O2S

Molecular Weight

258.30

References & Citations

[1]Cautain B, et al. Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling. PLoS One. 2016 Dec 9;11 (12) :e0167491.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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