LOM612
LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells[1].
Product Specifications
CAS Number
[2173232-79-4]
UNSPSC
12352005
Target
FOXO
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/LOM612.html
Purity
98.85
Solubility
DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(SN=C2N(C)C)C(C3=CC=CC=C31)=O
Molecular Formula
C13H10N2O2S
Molecular Weight
258.30
References & Citations
[1]Cautain B, et al. Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling. PLoS One. 2016 Dec 9;11 (12) :e0167491.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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