Ginsenoside Rg1
Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
Product Specifications
CAS Number
22427-39-0
Product Name Alternative
Panaxoside A; Panaxoside Rg1
UNSPSC
12352005
Hazard Statement
H302
Target
Amyloid-β; Apoptosis; NF-κB
Type
Natural Products
Related Pathways
Apoptosis; Neuronal Signaling; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Ginsenoside-Rg1.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : ≥ 100 mg/mL|H2O : 10 mg/mL (ultrasonic)
Smiles
[H][C@]12C(C)(C)[C@@H](O)CC[C@]1(C)[C@]3([H])[C@@]([C@@](CC[C@]4([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)(C)[C@]4([H])[C@H](O)C3)(C)C[C@@H]2O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O
Molecular Formula
C42H72O14
Molecular Weight
801.01
Precautions
H302
References & Citations
[1]Li N, et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40 (1) :9-17.|[2]Zhang L, et al. Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats via modulation of PPAR-γ/NF-κB signal pathway. Oncotarget. 2017 Jul 24;8 (33) :55384-55393.|[3]Wang P, et al. Effect of ginsenoside Rg1 on proliferation and differentiation of human dental pulp cells in vitro. Aust Dent J. 2012 Jun;57 (2) :157-65.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
RelA/p65
Available Sizes
Frequently Asked Questions
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